Uterine smooth muscle tumor of uncertain malignant potential (STUMP) ABOUT a CASE.

INTRODUCTION AND IMPORTANCE: Uterine smooth muscle tumor of uncertain malignant potential (STUMP) is rare tumor, and regarded as sub-classification in uterine smooth muscle tumors between benign and malignant criteria. They represent a heterogeneous group of rare tumors. PRESENTATION OF CASE: We report a case of a STUMP tumor in a fifty-three-year-old patient who underwent surgery for a hysterectomy. DISCUSSION: STUMP often presents with nonspecific clinical manifestation the only confirmatory examination is anatomopathological and may be supported by immunohistochemistry, hysterectomy is currently considered the gold standard of treatment. CONCLUSION: Uterine STUMP tumor represents a therapeutic dilemma. A multidisciplinary approach is mandatory.

Holoprosencephaly (HPE) : case report and review of the literature.

INTRODUCTION: Holoprosencephaly (HPE) is a complex brain malformation resulting from a medial cleavage defect of the prosencephalon into right and left hemispheres, occurring during early embryonic development. CASE PRESENTATION: We report an alobar holoprosencephaly diagnosed on imaging (obstetrical ultrasound) and revealed by a polymalformative syndrome in an 8-month-old infant. DISCUSSION: Holoprosencephaly affects the forebrain and face, causing neurological manifestations and facial anomalies of varying severity. HPE is a cerebral midline anomaly. CONCLUSION: Its fetal prognosis is extremely guarded, particularly for the alobar form.

Tubal adenocarcinoma: Report of 3 cases and review of the literature.

INTRODUCTION: Tumors of the uterine tube are rare pathologies representing less than 1 % of all gynecologic cancers; they are dominated by adenocarcinomas. Secondary metastatic forms are the most frequent, whereas primary tumors are very rare and represent only 10 %, which suggests that the fallopian tube is an organ with low oncogenic potential. REPORT OF TWO CASES: We report the two cases of a patients followed in the gynecology department C of the CHU IBN ROCHD CASA for a primary tubal adenocarcinoma. DISCUSSION: The diagnosis of its origin is difficult preoperatively, the treatment and staging are the same as for ovarian cancer. CONCLUSION: The treatment is also identical to the management of ovarian cancer, but their prognosis is better because they are most often diagnosed at an earlier stage.

Breast neurofibroma: A case report.

INTRODUCTION: Neurofibromatosis type 1 or Von Recklinghausen disease is a rare autosomal dominant hereditary disease with total penetrance. It is characterized by an extreme clinical variability that is also found within the same family. PRESENTATION OF CASE: We report a case of neurofibroma exceptional by its location in the breast in a 40-year-old woman with Von Recklinghausen disease, discovered by a breast nodule on self-examination. A biopsy-exeresis had concluded on the anatomopathological examination to the diagnosis of neurofibroma. DISCUSSION: Breast involvement in neurofibromatosis is extremely rare and possible. Rapid and adequate management of patients with Von Recklinghausen disease is essential in order to make the diagnosis early and to institute appropriate treatment as soon as possible, given the risk of possible malignant transformation. CONCLUSION: Diagnosis is essentially based on anatomopathological study. This confirms the diagnosis and rules out possible associated malignancy.

Neuroendocrine carcinoma of the breast: A case report and review of the literature.

INTRODUCTION: Neuroendocrine carcinomas mainly affect the bronchopulmonary system and the gastrointestinal tract. Mammary localizations are rare. They represent less than 0.1 % of all breast cancers and less than 1 % of neuroendocrine tumors. CASE REPORT: Our case concerns a 50-year-old female patient, who has presented for one year with a rapidly evolving, hard, right breast nodule without associated adenopathy. DISCUSSION: The diagnosis of certainty is based on histological study, and more particularly on immunohistochemical study. Studies concerning this entity are rare and include a small number of cases. We have described a case of triple negative neuroendocrine carcinoma with a high proliferation index. The study of larger series will allow us to better understand their histogenesis as well as their evolutionary profile. CONCLUSION: The treatment of endocrine tumors of the breast is mainly surgical. The indications for chemotherapy and radiotherapy are the same as for other breast cancers.

Ovarian cystic tumor composed of brenner tumor and stroma ovarii.

INTRODUCTION: Brenner's tumors are transitional cell ovarian tumors composed of mature cells similar to urothelial cells forming nests within a fibromatous stroma. CASE REPORT: In this observation we report the case of a brenner's tumor diagnosed in a 63 year old female patient. The positive diagnosis was difficult to retain. DISCUSSION: Brenner tumors are rare fibroepithelial ovarian tumors, representing 1 to 2 % of all ovarian tumors. They are almost always benign. CONCLUSION: The treatment is essentially surgical and the indication of chemotherapy remains debatable.

Desmoidfibromatosis of the breast after breast reduction: A case report and a review of the literature.

INTRODUCTION: Desmoids fibromatosis is a rare pathology whose definitive diagnosis is histological. Although it presents clinical and radiological similarities with breast carcinoma. CASE REPORT: In this observation, we report a case of desmoids fibromatosis diagnosed in a 51-year-old female patient. The positive diagnosis was difficult to retain. DISCUSSION: Desmoids fibromatosis remains a benign pathology with a high recurrence rate and a local aggressiveness requiring an enlarged lumpectomy with sufficient margins up to 3 cm. CONCLUSION: Radiotherapy remains a therapeutic option in addition to surgery in incomplete sections and in case of multiple recurrences. The place of medical treatments, in particular anti-estrogens, is not clearly defined.

Tubal adenocarcinoma in a case report.

INTRODUCTION: Tumors of the uterine tube are rare pathologies representing less than 1 % of all gynecologic cancers; they are dominated by adenocarcinomas. Secondary metastatic forms are the most frequent, whereas primary tumors are very rare and represent only 10 %, which suggests that the fallopian tube is an organ with low oncogenic potential. CASE REPORT: We report the case of a patient followed in the gynecology department C of the CHU IBN ROCHD CASA for a primary tubal adenocarcinoma, with a history of breast cancer. DISCUSSION: The diagnosis of its origin is difficult preoperatively, the treatment and staging are the same as for ovarian cancer. CONCLUSION: The treatment is also identical to the management of ovarian cancer, but their prognosis is better because they are most often diagnosed at an earlier stage.

Desmoid fibromatosis of the breast occurring after breast reduction surgery mimicking a carcinoma: A rare case report.

Introduction: Desmoid tumors are benign mesenchymal tumors developed at the expense of muscular fasciae and aponeuroses. The mammary localization is a rare entity, representing less than 0.2% of all breast tumors. It is characterized by a strictly local evolution and its tendency to recur without giving metastases. Its clinical and radiological presentation is similar to a breast carcinoma which is the main differential diagnosis. Case presentation: Patient aged 51 years, primigravida primiparous, followed for right breast cancer diagnosed at the age of 49 years for which she received a right mastectomy and axillary lymphnode dissection and contralateral breast reduction. It was a 4 cm infiltrating ductal carcinoma, SBR III Luminal B, 0 N+/20 N with presence of fibrous mastopathy without sign of malignancy at the left breast reduction specimen.The patient received adjuvant chemotherapy, external radiotherapy and hormone therapy.One year after surgery, the patient returned for a four x 2 cm left breast nodule in the upper medial quadrant. The biopsy confirmed the diagnosis of fibromatosis of the breast. A wide local excision was performed. Discussion: The etiology of this tumor is unknown, however, physical, hormonal and genetic factors play an important role in the development of desmoid tumor.The clinical presentation is similar to breast carcinoma, making it difficult to differentiate this tumor from breast carcinoma. Breast imaging techniques are not specific for desmoid fibromatosis. Treatment is based primarily on complete surgical excision. Conclusion: Breast fibromatosis is a rare entity, clinically and radiologically mimicking breast cancer. Only histology will provide the diagnosis. The treatment of choice is based on complete surgical excision with healthy safety margins.

Radiotherapy-induced uterine cacinosarcoma: A case report and review of the literature.

Radiation therapy is a very effective treatment modality for cervical cancer, but unfortunately, ionizing radiation is associated with many side effects, including secondary cancer formation. We report a case of carcinosarcoma of the uterus in a woman with a history of pelvic irradiation for cervical carcinoma. A review of the literature was performed to present the incidence, optimal management, and prognosis for post-radiation uterine carcinosarcoma.

Vaginal leiomyoma mimicking a Cystocele (report case).

INTRODUCTION AND IMPORTANCE: Leiomyoma, known as a disease of the uterus, composed of spindle-shaped smooth muscle fibers and collagenous stroma, is rarely encountered in other sites especially in the vagina. CASE PRESENTATION: We report, here, an exceptional case of a vaginal leiomyoma situated in the anterior vaginal wall suggesting in the first place a cystocele. The MRI objectified a rounded formation of the anterior wall of the vagina with regular contours highly suggestive of a vaginal leimyoma. The tumor was surgically removed by the vaginal route. The histopathologic examination confirmed the diagnosis of vaginal leiomyoma. CLINICAL DISCUSSION: Vaginal leiomyomas are commonly seen in women between the ages of 35 and 50 and are believed to be more common in Caucasian women. Although a rare tumor, vaginal leiomyomas may present with a variety of clinical features and may be mistaken preoperatively for a cystocele, urethrocele, Skene's duct abscess, Gartner's duct cysts, urethral diverticulum, vaginal cysts, cysts Bartholin's gland or a malignant vaginal tumor. The diagnosis is based on careful examination and preoperative imaging (ultrasonography and MRI). Removal of the tumor by vaginal route, wherever possible, with subsequent histopathological examination appears to be the optimum management plan. Although the lesion is benign, local recurrences following incomplete resection and sarcomatous changes have been reported. CONCLUSION: Vaginal leiomyoma is a rare benign tumor. The diagnosis is often made only postoperatively after resection of the mass. The tumors may be found in any location within the vagina but are most commonly located on an anterior wall. Imaging can confirm the vaginal origin of the lesion. Surgical excision is the treatment of choice. The diagnosis is based on the histological study of the tumor.

Primary ovarian fibroma in a postmenopausal woman: A case report.

INTRODUCTION: Primary ovarian leiomyoma is a rare benign tumor of the ovary seen in women between 20 and 65 years old. Clinical, ultasonographic and tumor marker data remain the best preoperative approach currently available for ovarian tumours. Only pathological examination can establish the diagnosis. CASE PRESENTATION: We describe a case of unilateral, ovarian leiomyoma. The abdomino-pelvic Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a left adnexial mass. A hysterectomy without adnexal preservation was performed, and histological examination revealed a leiomyoma arising primarily in the ovary. The diagnosis was confirmed immunohistochemically. DISCUSSION: The tumor may be asymptomatic or may manifest with lower abdominal pain associated to metrorrhagia like in our case. The definitive diagnosis of these lesions is difficult prior to surgical removal. Because there is no pathognomonic symptoms or characteristic imaging findings. The correct diagnosis of an ovarian leiomyoma is confirmed immunohistochemically. CONCLUSION: This rare tumor of the ovary should be considered in the differential diagnosis of solid ovarian masses. An immunohistochemical analysis is recommended for definitive diagnosis.

Corrigendum to "A rare case of unilateral axillary supernumerary breast (Radiology Case Reports 16 [2021] 2804-2807)".

[This corrects the article DOI: 10.1016/j.radcr.2021.06.074.].

A rare case of unilateral axillary supernumerary breast.

Polymastia or supernumerary breast is an anomaly of the embryonic development of the mammary gland resulting in ectopic breast tissue. We report an exceptional case of a unilateral axillary supernumerary breast in a 71-year-old patient which became enlarged after menopause. The diagnosis was confirmed on anatomopathological study which revealed no sign of malignancy otherwise. In our case, it was a proliferation of glandular tissue, without areola or nipple, rarely reported in the literature, and corresponding to Kajava class IV. The patient underwent surgical treatment in order to resolve the problem of aesthetic discomfort and to limit the risk of malignant transformation.

Risk factors and poor prognostic factors of preeclampsia in Ibn Rochd University Hospital of Casablanca: about 401 preeclamptic cases.

Preeclampsia is a gestational pathology that complicates 2 to 8% of pregnancies and is one of the major causes of maternal and fetal morbidity and mortality worldwide. The aim of this work was to study the epidemiological profile of preeclampsia in Casablanca and to identify risk factors as well as factors of poor maternal and fetal prognosis. 401 preeclamptic cases were collected in the gynecology-obstetrics "C" Service of Lalla Meryem Maternity of Ibn Rochd University Hospital of Casablanca (2010-2011) were included in this study and a statistical analysis with the SPSS software version (16.0) was performed. We used the Chi-2 test to analyze qualitative variables and Student's test and ANOVA (analysis of variance) for quantitative variables. The incidence of preeclampsia was (7.1%). The epidemiological profile was that of a primipara (57.6%), average age 30 years and (66.8%) of pregnancies were not followed. Multiparity was a factor of poor maternal prognosis (p = 0.007). The low gestational age and no prenatal care were factors of maternal as well as fetal prognosis. Risk factors frequently found in our patients were obesity (15.21%) and chronic hypertension (5.73%) as vascular-renal history; abortion (16.46%) and perinatal death (5.24%) as obstetric history. Preeclampsia is a common obstetric pathology in our context. Better prenatal care and early diagnosis could reduce its incidence.

[Haemorrhagic stroke of the brainstem secondary to postpartum eclampsia: about a case and literature review]. / Accident vasculaire cérébral hémorragique du tronc cérébral suite à une éclampsie du post partum: à propos d'un cas et revue de la littérature.

Strokes are rare but severe accidents during pregnancy and post-partum period. They are responsible for high mortality and morbidity rates. Pre-eclampsia, eclampsia, and strokes are significantly related. Endothelial dysfunction, alteration of brain self-regulation and severe hypertension are, probably, the cause of many strokes in pregnant women and during postpartum period. We report a case of hemorrhagic stroke of the brainstem in a nonmonitored 21-year old patient at 38 weeks pregnant admitted with severe preeclampsia complicated by eclampsia and then by haemorrhagic stroke of the brainstem on the second post-operative day after cesarean section performed due to suspicion of retroplacental haematoma arisen since her admission. Intracerebral hemorrhage is a rare but severe complication in post-partum women. Several studies are underway to fill the gaps of knowledge involved in the management of pre-eclamptic patients with neurological complications.

[Uterine rupture in a patient with bicornuate uterus at 12 weeks of amenorrhea: about a case]. / Rupture utérine sur utérus bicorne à 12 semaines d'aménorrhée: à propos d'un cas.

The incidence of uterine malformations affecting reproduction is difficult to assess. Their identification requires a specific assessment (hysterosalpingography, hysteroscopy, laparoscopy). Spontaneous fertility can be affected depending on the type of uterine abnormality. All these abnormalities can affect the evolution of pregnancy causing early and late miscarriage, ectopic pregnancy, threat of premature labour, premature labour, vascular pathologies during pregnancy and inadequate intra-uterine growth. Bicornuate uterus is the most common uterine malformation and represents about half of all uterine anomalies The occurrence of this type of pregnancy is associated with an increased risk of maternal mortality, but early diagnosis and proper monitoring can lead pregnancies to term on malformed uterus. Ultrasound screening should allow for a systematic identification of such cases in order to take the necessary preventive measures. We report a case of uterine rupture in a patient with unicervical bicornuate uterus at 12 weeks of amenorrhea.

[Meckel Gruber syndrome: about a rare case]. / Syndrome de Meckel Gruber: à propos d'un cas rare.

Meckel Gruber syndrome is a rare autosomal recessive polymalformation syndrome characterized by occipital encephalocele, polydactyly and cystic renal dysplasia. Ultrasound is, at present, the best tool for prenatal screening of this lethal polymalformation and diagnosys is confirmed by karyotyping. We here report a case of Meckel Gruber syndrome detected by ultrasound. Abortion was performed at 25 weeks of amenorrhoea.